Armodafinil vs Modafinil | Which one should I choose? -LA Weekly (2023)

Disclaimer: The content provided here is for educational purposes only. There is no medical advice, diagnosis or treatment. If anyone needs to use any of these smart drugs, they should consult a doctor first.

Armodafinil and modafinil are two nootropics that perform a similar function. Biologically, they work similarly to stimulants such as Concerta and Adderall by increasing dopamine levels in the brain. Both Armodafinil and Modafinil are FDA approved and used to treat excessive daytime sleepiness and improve wakefulness.

Still, there are slight differences between them that make people wonder, "Armodafinil vs. Modafinil, which is most effective?" This is a real concern for people suffering from conditions such as obstructive sleep apnea (OSA), narcolepsy or shift work disorder. The main purpose of taking medication is to relieve the symptoms of a condition without experiencing the side effects associated with the medication.

There are many factors that go into deciding whether to use Modafinil or Armodafinil, such as: How much does the medication cost? What chemicals are in the medication? Are both classified as Schedule IV non-narcotics?

Will I experience negative side effects?Which is the strongest? How long do they take to take effect and what is their half-life? All these questions and more are answered in this comprehensive Armodafinil vs Modafinil review. At the end of the article, you will know exactly which drug (aka nootropic) is best for you.

Modafinil and Armodafinil - a historical context

The drug Modafinil originally comes from France and was developed in the late 1970s by neurophysiologist Professor Michel Jouvet et al. Early in the research phase, it was found that the drug energized the participants and kept them awake for long periods of time.

Tested in patients with narcolepsy in 1986, modafinil was tested in a clinical trial for eight years and then approved in 1994 for the treatment of sleep disorders such as shift work.

In 1998, the drug modafinil was first brought to America and approved by the FDA for the treatment of narcolepsy; It is currently sold under the brand name Provigil by some pharmacies. It is worth noting that Modafinil is classified as a Schedule IV drug in the United States. In 2003, after the clinical trial, Modafinil was also approved for the treatment of other sleep disorders, such as: B. Obstructive sleep apnea caused by narcolepsy and shift work disorder.

After the introduction of Modafinil to the US prescription drug market, it quickly gained popularity among Internet entrepreneurs, CEOs and students for its performance-enhancing effects.

The result was the birth of the smart drug trend. When modafinil first hit the market, not many people knew about it, and the drug was hard to buy unless you were in certain circles. However, this is no longer the case, nowadays everyone can do itModafinil online kopen. Most suppliers offer free shipping and you will receive it in discreet packaging within 1 to 2 weeks.

The newest of the two drugs is the drug Armodafinil, which hit the market in 2007 following FDA approval. It is sold under the brand name Nuvigil and is considered a stimulant because of the long-lasting mental "excitement" it produces.

What are the benefits of using Modafinil and Armodafinil?

Research indicates that there are multiple benefits of taking the drugs modafinil and armodafinil for daytime sleepiness and sleep disorders such as narcolepsy, obstructive sleep apnea, and shift work. However, there are only a limited number of studies on the benefits of taking armodafinil throughout the day. Therefore, this section mainly focuses on the benefits of modafinil.

1) Modafinil eliminates fatigue

The main purpose of the drugsModafinilInArmodafinilis the elimination of fatigue. It gives users the energy they need to work longer. No matter how long someone has been awake, they still feel vital and motivated after taking these drugs.

2) Modafinil accelerates weight loss

If you are trying to lose weight, Modafinil is a great addition to your diet and exercise regimen. There are several factors that contribute to weight loss. As you have read, one of the conditions modafinil is prescribed for is obstructive sleep apnea. One of the leading causes of obstructive sleep apnea is obesity.

Armodafinil vs Modafinil | Which one should I choose? -LA Weekly (3)

In addition, suppressed appetite is one of the side effects of modafinil and armodafinil. For some who are not trying to lose weight, this can be seen as a negative side effect. But for those looking to lose a few pounds, a lack of appetite helps control food portions.

Finally, people who suffer from insomnia lack energy. This makes it difficult for them to motivate themselves to go to the gym. Modafinil is a powerful energy booster that gives an extra boost to people who want to lose weight during exercise.

3) Modafinil is not a stimulant

It's not uncommon for people to get nervous after their third cup of coffee. This anxious feeling can become very uncomfortable. Modafinil, on the other hand, stimulates the central nervous system, but not the adrenal glands. Coffee stimulates the adrenal glands and causes the symptoms associated with nervousness. Modafinil provides the focus and attention needed to get things done without the adrenaline rush.

4) Modafinil improves motivation

As you know, motivation is running out. People get excited after watching a motivational movie or hearing a motivational speech. However, this drive disappears within a few days and you settle back into your normal routine. One study found that participants taking modafinil became increasingly enthusiastic about their work, giving them the motivation they needed to keep going.

5) Modafinil eliminates the need for afternoon naps

Modafinil is especially beneficial for home workers. People find it hard to work from home because once they feel the desire to take a nap, it's easy to give in and go to bed for 20 minutes. Unfortunately, those 20 minutes turn into an hour or two for most people, and time is wasted sleeping when you could have been doing something more productive. Modafinil keeps you so focused and alert during the day that you don't feel like taking a nap in the middle of the day.

6) Modafinil improves mood

Peer-reviewed studies concluded that Modafinil induces a euphoric feeling. For this reason, it is often prescribed as an adjunctive therapy to treat patients with depression.

Armodafinil vs Modafinil | Which one should I choose? -LA Weekly (4)

7) Modafinil can reduce addiction to hard drugs

Research suggests that modafinil works well for people struggling with drug addictions such as cocaine and amphetamines. Therefore, it is currently considered as an adjunctive therapy in hard drug addiction.

Armodafinil vs Modafinil: Does It Treat Shift Work Insomnia And Obstructive Sleep Apnea?

Both Modafinil and Armodafinil medications are effective treatmentsshift work disorderand obstructive sleep apnea. Still, clinical studies suggest that armodafinil lasts longer after ingestion, but the two drugs modafinil and armodafinil are considered similar in their safety in the treatment of excessive sleepiness. Research suggests that higher concentrations of armodafinil occurred in participants' bodies. This allows Armodafinil to be slightly more potent than Modafinil.

Armodafinil is absorbed by the body immediately after taking it in case of excessive drowsiness. The maximum effect is achieved within 2 hours after taking the drug on an empty stomach. After eating food, the maximum effect occurs 2-4 hours later.

The half-life of armodafinil is approximately 20 hours. The half-life of modafinil is between 10 and 12 hours, but it can stay in the body for up to 15 hours. Therefore, armodafinil has a longer half-life.

A data analysis concludes that the drugs armodafinil and modafinil are effective treatments for conditions associated with excessive sleepiness and do not have negative effects on the central nervous system.

What information should I give my doctor before taking armodafinil and modafinil?

Before taking the drugs armodafinil and modafinil for excessive sleepiness, make sure it's safe for you. It is therefore important that you seek advice from your doctor (diagnosis or treatment) and tell him if you suffer from any of the following conditions:

  • alcohol or drug addiction
  • psychosis or mental illness
  • heart disease
  • high bloodpressure
  • A previous heart attack
  • Mitralklappenprolaps
  • kidney disease
  • liver disease

There is no evidence that 200mg (one of the most popular doses) of the drugs armodafinil and modafinil will have any negative effects on an unborn baby. In any case, women should inform their doctor if they are pregnant or plan to become pregnant. It is not known whether armodafinil or modafinil contaminates breast milk; Therefore, nursing mothers should tell their doctor that they are breastfeeding before taking the drug.

What are the ingredients in Armodafinil and Modafinil?

The main ingredients in armodafinil are povidone, stearate, magnesium, monohydrate, lactose, sodium and croscarmellose. The main ingredients in modafinil are magnesium stearate, povidone, croscarmellose sodium, pregelatinized starch, microcrystalline cellulose, and lactose monohydrate.

Armodafinil vs Modafinil | Which one should I choose? -LA Weekly (5)

How should I take Armodafinil and Modafinil?

All the information you need to take Armodafinil can be found on the prescription label. It is important that you take the medication exactly as prescribed and that you do not take more or less than you should. As mentioned earlier, Armodafinil has an addictive nature; Therefore, it is important that you do not share the drug with others, especially if they have a history of addiction or substance abuse.

Read all patient guides, data and factsheets for the prescription drugs offered and consult your pharmacist or doctor if you are unsure. Patients with excessive sleep disturbances should take one 250 mg tablet once a day.

It is usually taken in the morning as a protective measure against daytime sleepiness. For sleep disturbances during shift work, armodafinil should be taken one hour before the start of the shift. You can take armodafinil before or after meals.

Doctors usually prescribe armodafinil for 12 weeks. If you are taking armodafinil to treat conditions such as obstructive sleep apnea. You may also have been given a CPAP (continuous positive airway pressure machine) device. aCPAPkeeps your airways open to prevent them from collapsing during sleep. Unless your doctor tells you to stop using the device, you should continue to do so while taking armodafinil or you could experience negative side effects. Armodafinil cures or treats the underlying causes of the condition.

You must take modafinil orally once a day. It can be taken before or after meals. Choose the best time to take Modafinil and stick to it. If you need to change the time, it is important to discuss this with your doctor beforehand. You should also let your doctor know if your shifts start at different times of the week.

For modafinil to be most effective, you need to find the right dosage. Modafinil works best when you take between 100mg, 150mg and 200mg per day. However, 50mg may not have any effect in some people because it is such a low dosage. Experts advise, if you have just started taking the drug, start with a single dose of 50mg, 150mg or 100mg and increase the dose over time.

Read our reviewModalert rating(one of the best generic modafinil products on the market)

What should I do if I miss a dose of armodafinil?

As soon as you realize you have missed a dose, take the medicine. However, if it's late in the day, don't take it. If you realize you missed your dose of armodafinil just before bed, wait until the next day to take it again.

Drug Interactions and Armodafinil?

It is not recommended to combine armodafinil with drugs that cause drowsiness, as this may enhance the effects. Consult your doctor before taking medication for seizures, depression, anxiety, muscle relaxants, narcotics, or sleeping pills. In addition, Armodafinil can interact with herbal products, vitamins, over-the-counter medications, and other prescription medications. Therefore, make sure you get medical advice before taking armodafinil or modafinil.

Read oursModalert versus Modvigil versus Waklert versus Artvigil: in-depth assessmentfor more information on the generic brands of Modafinil.

Physical dependence on armodafinil and modafinil

It is also possible that patients may become physically dependent on armodafinil and modafinil for their wakefulness-promoting effects. We speak of physical dependence when there is a psychological adjustment as a result of repeated drug use.

Armodafinil vs Modafinil | Which one should I choose? -LA Weekly (6)

Physical dependence manifests as withdrawal symptoms when a patient's dose of armodafinil or modafinil is reduced or when the drug is discontinued. These symptoms include atrial fibrillation, aggression, confusion, vomiting, nausea, chills, sweating, tremors, suicidal ideation, depression, body aches, insomnia, fatigue, and headache.

Armodafinil- and Modafinil Tolerance Levels

Compatibility between Armodafinil and Modafinil occurs when Armodafinil or Modafinil has been taken for a long period of time and the biological response is no longer as effective. To get the same effects, the dosage has to be increased.

Possible overdose of armodafinil and modafinil

There have been reports of fatal overdoses with armodafinil or modafinil alone and in combination with other drugs. Symptoms suggestive of an overdose of armodafinil and modafinil include chest pain, high blood pressure, diarrhea, nausea, hallucinations, confusion, disorientation, agitation, insomnia, shortness of breath, and anxiety.

When considering armodafinil vs modafinil, don't worry about the minor side effects; However, if you experience more serious side effects of armodafinil or modafinil, make an appointment with your doctor right away.

What are the differences between Armodafinil and Modafinil?

The chemical structure of armodafinil differs slightly from that of modafinil. The Food and Drug Administration has approved armodafinil as the R-enantiomer of modafinil. An enantiomer is a molecule that reflects another compound. Although they are similar, they are not exactly the same. In other words, they perform the same function, but there are differences between them. For example, the left and right hands have the same function, they have a similar biological structure, but they are not exactly the same.

Armodafinil vs Modafinil: What's The Price Difference?

Armodafinil is available generically under the brand name Nuvigil. Armodafinil is covered by health insurance and Medicare. The average retail price of Armodafinil is over $500 for 30 tablets. However, if you have a SingleCare discount card, you can buy 30 tablets of Armodafinil for $277.

Armodafinil vs Modafinil | Which one should I choose? -LA Weekly (7)

Modafinil is slightly more expensive compared to armodafinil under insurance; In addition, it depends on which insurance you have taken out whether the insurance cover exists. 30 tablets can cost over $600. If you have a SingleCare savings card, you can buy 30 modafinil tablets for between $35 and $280. ​​However, this depends on the pharmacy you use.

Where can I buy Armodafinil and Modafinil?

You canModafinil online kopenat one of the following authorized dealers: |Visit the website

Armodafinil vs Modafinil | Which one should I choose? -LA Weekly (8)

Before placing a bulk order, you will receive a free sample so that you can determine if Modafinil is the right drug for you. The company ships worldwide and offers a 20% discount if you pay with bitcoin (Get started with bitcoin atCoinbase. com) |Visit the website

They have billed themselves as the top online modafinil seller. Your package will be shipped from India and delivered directly to your home. They offer a 33% discount if you pay with bitcoin (Get started with bitcoin atCoinbase. com). In the event that your product does not arrive, you will receive a full refund.

Armodafinil vs Modafinil | Which one should I choose? -LA Weekly (9) |Visit the website

This online pharmacy delivers generic smart pills from India to your doorstep. They ship to many countries including America, England and Australia, but not every country in the world.

Armodafinil vs Modafinil | Which one should I choose? -LA Weekly (10) |Visit the website

They are the only US-run modafinil supplier in the world. If you're ever in doubt, they offer year-round customer support. Plus, they offer some of the cheapest prices on the market.

Armodafinil vs Modafinil | Which one should I choose? -LA Weekly (11)

Is It Safe To Buy Modafinil Online?

Yes, that is 100% safemodafinil online kopen,Let me tell you why. Each recommended online retailer has been thoroughly vetted to ensure they are licensed pharmacies selling certified products that are properly manufactured.

They are all reputable organizations where you can shop with the same confidence as you would at your local pharmacy. In addition, your credit card details, address and telephone number are protected by the secure online systems. Check out our comprehensive guide on "Modafinil online kopen" For more information.

Armodafinil, on the other hand, is not that easy to get your hands on unless you do it yourselfget a prescriptionfrom your doctor.

Armodafinil vs. Modafinil and Substance Abuse

It is also important to note that there have been reports of armodafinil abuse and armodafinil dependence in patients treated with the drug. Patterns of abuse include repeated use of armodafinil and modafinil, or taking large doses to induce a euphoric mood. There have also been reports of medication diversion, with patients taking armodafinil after their doctor advised against it and getting prescriptions from multiple doctors.

Misuse of armodafinil carries a risk of overdose which may cause: abdominal pain, vomiting, flushed skin, loss of coordination, decreased appetite, agitation, hyperactivity, dilated pupils, sweating, tachypnoea, hallucinations, delirium, seizures, high blood pressure , chest pain , tremors, dystonia, headache, nausea, anxiety, dizziness, restlessness, insomnia and tachycardia.

When abused, modafinil leads to feelings of euphoria, changes in feelings, thinking and perception. Due to the abuse potential of armodafinil and modafinil, physicians are advised to closely monitor patients with a history of drug or stimulant use (cocaine, amphetamine, or methylphenidate). Signs of abuse include addictive behavior or a dose increase.

Armodafinil vs Modafinil: What Are The Most Common Side Effects?

There are several side effects associated with armodafinil and modafinil. The most common are the following:

  • insomnia
  • dizziness
  • nausea
  • Headache

In addition, Modafinil has been reported to cause side effects such as:

  • backache
  • Diarrhea
  • Stuffy nose
  • nervousness

Armodafinil and modafinil can also cause anxiety, indigestion, dry mouth, and weight loss due to decreased appetite. However, these symptoms are rare. More serious side effects include allergic reactions such as shortness of breath and rash. There have also been reports of psychiatric side effects such as psychosis and depression due to armodafinil.

It is not recommended that armodafinil and modafinil be taken by anyone under the age of 17 or if you have any of the above conditions such as high blood pressure. In addition, you should consult your doctor for advice on diagnosis or treatment

Armodafinil vs Modafinil What is the final conclusion?

As you have read, Armodafinil and Modafinil have similar functions, both work as effective treatments for conditions such as Obstructive Sleep Apnea and Shift Sleep Disorder, and are also considered effective cognitive performance enhancers.

Whether you choose armodafinil or modafinil depends on which differences are most important to you. The side effects are generally the same. Research suggests that armodafinil is slightly more effective than modafinil because its effects are stronger.

As for the benefits of both drugs, there is a lot more research highlighting the benefits of Modafinil vs. Armodafinil. If you are concerned about cost, Modafinil will definitely be cheaper if you buy it from one of the reputable online retailers.

Scientific, or Nuvigil (Modafinil) is better than Modafinil is inconclusive; However, if your main concern is potency, with the above in mind, you should try both Armodafinil and Modafinil to see which works best for you. Finally, if you are looking for a cheap, private and convenient way to buy Armodafinil and Modafinil,Do your shopping onlineis your best option.

Ad Disclosure: We may receive compensation for some links in our stories. Thank you for supporting LA Weekly and our advertisers.


Do you have to take armodafinil every day? ›

It is usually taken once a day. If you are taking armodafinil to treat narcolepsy or OSAHS, you will probably take it in the morning. If you are taking armodafinil to treat shift work sleep disorder, you will probably take it 1 hour before the start of your shift. Take armodafinil at around the same time every day.

Is modafinil better than armodafinil review? ›

The efficacy of armodafinil was found to be comparable to 200 mg of modafinil in maintaining wakefulness. The safety profile of armodafinil was found to be similar to modafinil. Both modafinil and armodafinil caused a slight increase in liver enzymes, and armodafinil caused a slight increase in blood urea nitrogen.

Do you have to take Nuvigil everyday? ›

Nuvigil (armodafinil) is a brand-name drug that's prescribed for improving wakefulness and sleepiness due to narcolepsy, obstructive sleep apnea, or shift work disorder. Nuvigil comes as a tablet that's typically taken once per day. The dosage can vary depending on what condition the drug is used to treat.

What are the advantages of armodafinil over modafinil? ›

Armodafinil has been shown to improve wakefulness in patients with excessive sleepiness (ES) associated with treated obstructive sleep apnoea, shift work disorder or narcolepsy. In comparison with modafinil, armodafinil maintains higher plasma concentrations later in the day in healthy subjects.

Can you take armodafinil intermittently? ›

The intermittent use of armodafinil in patients with SWD did not diminish its efficacy. Patients with SWD reported baseline levels of fatigue on the BFI similar to those reported by patients with treated OSA, and demonstrated similar reductions in fatigue throughout the study.

Is it okay to skip a day of modafinil? ›

If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses. If you miss a dose of modafinil and you remember it before 12:00 noon the same day, take the missed dose as soon as possible.

Is armodafinil stronger than modafinil? ›

If the same doses of modafinil and armodafinil are given in the morning, the afternoon blood levels of armodafinil are considerably higher. For this reason, a morning dose of armodafinil (150–250 mg) may control afternoon sleepiness better than modafinil.

Does armodafinil make you focus? ›

Armodafinil (Nuvigil) can change the way you focus, think, and react. While the medication can improve wakefulness, some people with extreme sleepiness might still have a hard time staying awake while taking armodafinil (Nuvigil).

Does armodafinil increase dopamine? ›

Armodafinil may work by increasing the amount of dopamine (a chemical neurotransmitter that nerves use to communicate with each other) in the brain by reducing the reuptake of dopamine into nerves. The FDA approved armodafinil in June 2007.

Can you take armodafinil as needed? ›

For narcolepsy and obstructive sleep apnea, take this medication by mouth as directed by your doctor, usually once daily in the morning. If you are using armodafinil for shift work sleep disorder, take it as directed by your doctor, usually once a day 1 hour before you start your work shift.

Can armodafinil help chronic fatigue? ›

Armodafinil has an average rating of 7.3 out of 10 from a total of 39 reviews for the off-label treatment of Chronic Fatigue Syndrome. 64% of reviewers reported a positive experience, while 13% reported a negative experience.

How many hours does armodafinil last? ›

After reaching peak plasma levels, concentrations of armodafinil declined monophasically, with a mean elimination half-life of around 15 hours.

Which lasts longer modafinil or armodafinil? ›

Armodafinil (NuVigil) is the R enantiomer of modafinil and has a longer half-life than L-modafinil. The usual dose is 150 mg or 250 mg daily. Modafinil (Provigil) is the racemic form of the medication (L and R enantiomers), and after a few hours only R-modafinil remains in the circulation.

Does armodafinil improve memory? ›

Effects on memory and attention

Compared with placebo, armodafinil significantly improved the quality of episodic secondary memory across the first four tests (09:30, 11:30, 13:30, 15:30) at all study visits (P < 0.05; Fig.

What is the risk of armodafinil? ›

This medicine may cause serious allergic reactions, including anaphylaxis, angioedema, or certain skin conditions (Stevens-Johnson syndrome). These reactions can be life-threatening and require immediate medical attention.

Can armodafinil be stopped abruptly? ›

If you suddenly stop using this medication, you may have withdrawal symptoms (such as shaking, sweating, chills, nausea, vomiting, confusion). To help prevent withdrawal, your doctor may lower your dose slowly. Withdrawal is more likely if you have used armodafinil for a long time or in high doses.

How long can you take armodafinil for? ›

Armodafinil was also generally well tolerated whether used daily (by patients with treated OSA or narcolepsy) or intermittently (by those with SWD) for up to 2 years; however, increased monitoring of blood pressure may be appropriate in patients on armodafinil.


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